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Biostimulators offer an elegant, evidence-based approach to rejuvenation — improving skin quality from within rather than masking symptoms on the surface. Whether through hyperdilute Radiesse or autologous PRFM, these treatments help restore youthful structure, support vascular health, and improve tone and texture in a subtle, natural way. They are especially appealing to patients seeking long-term skin regeneration with minimal risk of overfilled or “done” appearances.
Biostimulators are next-generation injectables designed to awaken your skin’s own regenerative potential. Rather than simply filling or plumping, they stimulate fibroblasts — the cells responsible for collagen, elastin, and structural proteins — to gradually restore firmness, elasticity, and natural lift. The result is refreshed, resilient skin that continues to improve for months after treatment, with benefits that can last up to two years.
Hyperdilute Radiesse®
When Radiesse® (a calcium-based gel) is hyperdiluted, it transforms from a volumizer into a true collagen biostimulator. This refined approach strengthens the skin from within, improving texture, tone, and tightness in areas such as the neck, lower face, and décolleté. Over time, Radiesse encourages your body to rebuild its own supportive collagen network — revealing skin that looks smoother, firmer, and more luminous.
Autologous Biostimulation with PRFM
Harnessing your body’s own growth factors, PRFM (Platelet-Rich Fibrin Matrix) rejuvenates the skin from within. A small blood sample is processed to concentrate platelets within a fine fibrin matrix that gradually releases regenerative proteins, promoting collagen renewal and long-lasting skin revitalization. The result is smoother texture, softened fine lines, and restored radiance—beautifully enhanced when combined with other regenerative treatments.
what can that do for me?
Biostimulators are advanced injectables that encourage your skin to produce new collagen in its deeper layers. Over several weeks to months, this process creates subtle, natural-looking fullness and improved elasticity — without an “overfilled” appearance.
Boosts collagen and elastin production, helping tighten skin and smooth crepiness.
Enhances firmness while softening fine lines and wrinkles.
Results develop gradually and can last 2 years or longer with proper maintenance.
Ideal for restoring age-related volume loss in areas such as the temples, cheeks, jawline, and nasolabial folds.
Creates a refreshed, lifted look without surgery or downtime.
Also used for skin tightening on the décolleté, upper arms, abdomen, or buttocks (often called a “Sculptra butt lift”).
For younger clients, biostimulators can preserve collagen and help maintain youthful structure over time.
Biostimulators can be used in multiple areas where collagen loss is common, including the cheeks, jawline, temples, lower face (such as smile lines and marionette lines), hands, neck, and décolletage.
Biostimulators such as Hyperdilute Radiesse® work gradually by stimulating your skin to produce new collagen and elastin, so results develop over time rather than immediately. Most clients begin to notice improved tone and firmness within 4–6 weeks, with continued enhancement over the following 3–6 months as collagen remodeling progresses.
Because the results come from your body’s own regenerative response, improvements look natural, subtle, and long-lasting—typically maintaining their effect for 12 to 24 months depending on individual factors such as age, skin quality, and lifestyle.
The number of treatments depends on your skin condition, goals, and the level of correction desired. Most clients achieve noticeable improvement with a series of two to three sessions, spaced about 3 months apart to allow for optimal collagen stimulation and remodeling.
After your initial series, maintenance treatments once or twice a year can help sustain and even enhance your results as your skin continues to age naturally. During your consultation, we’ll create a personalized treatment plan tailored to your unique skin needs and desired outcome.
Results from biostimulators such as Hyperdilute Radiesse® are long-lasting, as they work by stimulating your body’s own collagen and elastin production. Most clients enjoy visible improvement for 24 months, and in some cases even longer, depending on factors such as age, skin quality, metabolism, and lifestyle.
While your newly generated collagen is lasting, your skin will continue to age naturally over time. Periodic maintenance treatments—usually once or twice a year—can help preserve your results and keep your skin firm, lifted, and radiant.
Downtime is minimal. Mild swelling or bruising may occur for a few days, but most clients resume normal activities right away.
They’re ideal for individuals seeking natural-looking improvements in skin quality and firmness without adding significant volume. A consultation will confirm if this treatment is right for you.
Yes. They complement treatments like Botox, dermal fillers, and skin resurfacing for a more comprehensive rejuvenation plan.
At Speak Beauty Studios, we proudly offer Radiesse, our favorite biostimulator. Pricing is as follows:
Per Syringe: $800
Two Syringe Package: $1,400
Four Syringe Package: $2,500 (syringes can be split and used at follow-up sessions)
During your consultation, we’ll determine the number of syringes needed to achieve your desired results and create a customized treatment plan.
